back Articles Published by TTURC Researchers at Yale University Steinberg, M.A. , Potenza, M.N. , McLaughlin, S. , Wu, R. , Hemstock, D. , Lavelle, E.T. , Rounsaville, B.J. & O'Malley, S.S. (October, 2000). Disordered Gambling and Excessive Tobacco Use: Addiction Spectrum Behaviors?. National Conference on Problem Gambling. Stevens, T.R. , Krueger, S.R. , Fitzsimonds, R.M. & Picciotto, M.R. (Nov 2003). Neuroprotection by Nicotine in Mouse Primary Cortical Cultures Involves Activation of Calcineurin and L-Type Calcium Channel Inactivation.. Journal of Neuroscience, 23(31), 10093-10099. Potenza, M.N. , Steinberg, M.A. , McLaughlin, S. , Wu, R. , Lavelle, E.T. , Rounsaville, B.J. , O'Malley, S.S. & Hemstock, D. (May, 2000). Disordered gambling and excessive tobacco use: Addiction spectrum behaviors?. Society of Biological Psychiatry Annual Convention, see also Biol Psychiatry 47(8S): 156s. King, S.L. , Grady, S.R. , Marks, M.J. , Caldarone, B.J. , Koren, A. , Mukhin, A. , Collins, A.C. & Picciotto, M.R. (May 2003). Conditional Expression in Corticothalamic Efferents Reveals a Developmental Role for Nicotinic Acetylcholine Receptors in Modulation of Passive Avoidance Behavior. Journal of Neuroscience , 23(9), 3837-3843. McKee, S. , O'Malley, S.S. , Salovey, P. , Krishnan-Sarin, S. & Mazure, C. (March 2005). Perceived risks and benefits of smoking cessation: Gender-specific predictors of motivation and treatment outcome.. Addictive Behaviors, 30(3), 423-35. McKee, S. , O'Malley, S.S. , Salovey, P. , Krishnan-Sarin, S. & Mazure, C. (March 2005). Perceived risks and benefits of smoking cessation: Gender-specific predictors of motivation and treatment outcome.. Addictive Behaviors, 30(3), 423-35. Potenza, M.N. , Steinberg, M.A. , McLaughlin, S. , Hemstock, D. , Wu, R. , Lavelle, E.T. , Rounsaville, B.J. & O'Malley, S.S. (June, 2000). Characteristics of individuals with disordered gambling reporting excessive tobacco use. College on Problems of Drug Dependence Annual Meeting, see also Drug Alcohol Dependence 60s1: s173-s174. Ferrari, R. , Le Novere, N. , Picciotto, M.R. , Changeux, J.-. & Zoli, M. (Jun 2002). Acute and prolonged changes in dopamine mesoaccumbens pathway after systemic or local single nicotine injections. European Journal of Neuroscience, 15(11), 1810. Salovey, P. & Williams-Piehota, P. (Jan 2004). Field experiments in social psychology: Message framing and the promotion of health protective behaviors. American Behavioral Scientist, Vol 47(5), 488-505. George, T.P. , Vessicchio, J.C. , Termine, A. , Jatlow, P. , Kosten, T.R. & O'Malley, S.S. (Jan 2003). A preliminary placebo-controlled trial of selegiline hydrochloride for smoking cessation. Biological Psychiatry, Vol 53(2), 136-143. Brunzell, D.H. , Russell, D.S. & Picciotto, M.R. (In Press). In vivo nicotine treatment regulates mesocorticolimbic CREB and extracellular regulated kinase signaling in C57B1/6J mice. Journal of Neurochemistry. Caldarone, B.J. , Karthigeyan, K. , Harrist, A. , Hunsberger, J. , Wittmack, E.K. , King, S.L. , Jatlow, P. & Picciotto, M.R. (In Press). Effects of oral amitriptyline in three animal models of depression in C57BL6J mice. Psychopharmacology. Jatlow, P. , McKee, S. & O'Malley, S.S. (In Press). Correction of urine cotinine concentrations for cotinine excretion: Is it useful?. Clin Chem. Steward, W. , Schneider, T.R. , Pizarro, J. & Salovey, P. (In Press). Need for cognition moderates responses to framed smoking cessation messages. Journal of Applied Social Psychology. Toll, B.A. , Cooney, N. , McKee, S. , Cooney, J.L. , Blakeslee, A.N. & O'Malley, S.S. (In Press). Analysis of the correspondence of Interactive Voice Recognition assessment with Timeline Followback for alcohol use and cigarette smoking. Alcoholism: Clinical and Experimental Research, 27 (5), Supplement, 77S. Baker, T.B. , Hatsukami, D.K. , Lerman, C. , O'Malley, S.S. , Shields, A. & Fiore, M.C. (Dec. 2003). Transdisciplinary science applied to the evaluation of treatments for tobacco use. Nicotine & Tobacco Research , 1, 589-99. Nash, J.M. , Collins, B.N. , Loughlin, S.E. , Solbrig, M. , Harvey, R. , Krishnan-Sarin, S. , Unger, J.B. , Miner, C. , Rukstalis, M. , Shenassa, E. , Dube, C. & Spirito, A. (Dec 2003). Training the transdisciplinary scientist: A general framework applied to tobacco use behavior. Nicotine and Tobacco Research, 5(Suppl1), S41-S53. Brunzell, D.H. , Chang, J.R. , Schneider, B. , Olausson, P. , Taylor, J.R. & Picciotto, M.R. (2005). β2 Subunit-containing nicotinic acetylcholine receptors are involved in nicotine-induced increases in conditioned reinforcement but not progressive ratio responding for food in C57BL/6 mice. Psychopharmacology, Aug 13, 1-11. Sacco, K.A. , Termine, A. , Seyal, A.A. , Dudas, M.M. , Vessicchio, J.C. , Krishnan-Sarin, S. , Jatlow, P. , Wexler, B.E. & George, T.P. (2005). Effects of Cigarette Smoking on Spatial Working Memory and Attentional Deficits in Schizophrenia: Involvement of Nicotinic Receptor Mechanisms.. Archives of General Psychiatry., 62, 649-659. George, T.P. & O'Malley, S.S. (2004 Jan). Current pharmacological treatments for nicotine dependence.. Trends in Pharmacological Success, 25(1), 42-8. Krishnan-Sarin, S. , Meandzija, B. & O'Malley, S.S. (2003 Dec). Naltrexone and nicotine patch in smoking cessation: A preliminary study. Nicotine and Tobacco Research, 5(6), 851-7. Baker, T.B. , Hatsukami, D.K. , Lerman, C. , O'Malley, S.S. , Shields, A. & Fiore, M.C. (2003). Tobacco treatment evaluation: Achieving transdiciplinary integration. Presentation at the Society for Research on Nicotine and Tobacco Annual Meeting. Brunzell, D.H. , Russell, D.S. & Picciotto, M.R. (2003). Nicotine modulates activity of the mitogen activated protein kinase (mapk) signaling pathway in mouse. Society for Research on Nicotine and Tobacco Annual Meeting. Brunzell, D.H. , Russell, D.S. & Picciotto, M.R. (2003 ). In-vivo nicotine regulates mesocorticolimbic CREB and ERK signaling in C57Bl/6J mice. Journal of Neurochemistry, 84(6), 1431-41. George, T.P. , Vessicchio, J.C. , Termine, A. , Jatlow, P. , Kosten, T.R. & O'Malley, S.S. (2003). A Preliminary Placebo-Controlled Trial of Selegiline Hydrochloride for Smoking Cessation. Biological Psychiatry, 53, 136-143. Krishnan-Sarin, S. , Cavallo, D. , McKee, S. & George, T.P. (2003). Acute tobacco abstinence effects in adolescents: Influence of sex. Society of Research on Nicotine and Tobacco Annual Meeting. Krishnan-Sarin, S. , Cavallo, D. , McKee, S. & George, T.P. (2003). Acute tobacco abstinence effects in adolescents: influence of sex. Society for Research on Nicotine & Tobacco Annual Meeting. Liu, J. , Caldarone, B.J. , King, S.L. & Picciotto, M.R. (2003). Nicotine-ethanol in mouse models of anxiety . Society for Research on Nicotine and Tobacco Annual Meeting. Mazure, C. , O'Malley, S.S. , Perkins, K. , McKee, S. , Krishnan-Sarin, S. , Pomerleau, C.S. & Allen, S.S. (2003 ). Sex-specific effects in nicotine withdrawal: the role of psychiatric, cognitive and hormonal factors. Society of Research on Nicotine and Tobacco Annual Meeting. McKee, S. , Maciejewski, P. , Krishnan-Sarin, S. , Mazure, C. & O'Malley, S.S. (2003). Sex differences in tobacco withdrawal: interaction with alchohol and depression diagnoses. Society for Research on Nicotine and Tobacco Annual Meeting. McKee, S. , Maciejewski, P. , Krishnan-Sarin, S. , Mazure, C. & O'Malley, S.S. (2003). Sex differences in tobacco withdrawal: Interactions with alcohol and depression. Society for Research on Nicotine and Tobacco Annual Meeting. Picciotto, M.R. (2003). Nicotine as a modulator of behavior: Beyond the inverted U. Trends in Pharmacological Success, 24, 493-499. Staley, J. , Petrakis, I. , Krishnan-Sarin, S. , Tamagnan, G. , Perry, E. , Seibyl, J. , O'Malley, S.S. & Krystal, J.H. (2003). Correlation between severity of nicotine dependence and benzodiazepine receptor binding in alcoholics. Society for Research on Nicotine and Tobacco Annual Meeting. Balogh, S.A. , Owens, J.C. , Labarca, C. , Lester, H.A. , Picciotto, M.R. , Wehner, J.M. & Collins, A.C. (2002). Nicotine and ethanol-induced hypothermia in ß-4 and ß-2 nicotinic receptor subunit mutant mice. Research Society on Alcoholism Annual Meeting. Balogh, S.A. , Picciotto, M.R. , Paylor, R. , Booker, T.K. , Beaudet, A. , Heinemann, S. , Collins, B.N. & Wehner, J.M. (2002). Contextual fear conditioning in neuronal nicotinic receptor null mutant mice: Effects of nicotine and ethanol. Society for Neuroscience Abstract, 28. Brunzell, D.H. , Russell, D.S. & Picciotto, M.R. (2002). Effects of oral nicotine exposure on the mitogen-activated protein kinase (MAPK) signaling pathway. Society for Neuroscience Abstract, 28. Caldarone, B.J. & Picciotto, M.R. (2002). Knockout mice lacking the ß-2 subunit of the nicotinic receptor are insensitive to the tricyclic antidepressant amitriptyline. Presentation at Jackson Laboratories. Caldarone, B.J. , Karthigeyan, K. & Picciotto, M.R. (2002). Behavioral responses to a tricyclic antidepressant in knockout mice lacking the ß-2 subunit of the nicotinic receptor . Society for Neuroscience Abstract, 28. Fujita, M. , Seibyl, J. , Vaupel, D. , Tamagnan, G. , Early, M. , Zoghbi, S. , Baldwin, R. , Horti, A. , Koren, A. , Mukhin, A. , Khan, S. , Bozkurt, A. , Kimes, A. , London, E. & Innis, R.P. (2002). Whole body biodistribution, radiation-absorbed dose and brain SPET imaging with [123I]5-I-A-85830 in healthy human subjects. European Journal of Nuclear Medicine, 29, 183-190. King, S.L. , Caldarone, B.J. & Picciotto, M.R. (2002). Mice lacking ß-2 subunit-containing nicotinic acetylcholine receptors show reduced anxiety-like behavior. Society for Neuroscience Abstract, 28. Land, M. , McKee, S. & O'Malley, S.S. (2002). Why smokers switch from regular to light/ultra light cigarettes: A qualitative analysis of examining gender effects. Society for Research on Nicotine and Tobacco Annual Meeting. Lerman, C. , Shields, P.G. , Wileyto, P. , Audrain, J. , Pinto, A. , Hawk, L. , Krishnan-Sarin, S. , Niaura, R.S. & Epstein, L.H. (2002). Pharmacogenetic investigation of smoking cessation treatment. Pharmacogenetics, 12(8), 627-634. Owens, J.C. , Balogh, S.A. , Labarca, S.A. , Lester, H.A. , Picciotto, M.R. , Wehner, J.M. & Collins, A.C. (2002). The effects of ethanol on acoustic startle are modulated by the neuronal nicotinic receptor ß-4 subunit. Research Society on Alcoholism Annual Meeting. Picciotto, M.R. & Corrigall, W.A. (2002). Neuronal systems underlying behaviors related to nicotine addiction: Neural Circuits and Molecular Genetics. Journal of Neuroscience, 22(9), 3338-3341. Picciotto, M.R. , Brunzell, D.H. & Caldarone, B.J. (2002). Effect of nicotine and nicotine receptors on anxiety and depression. Neuroreport, 13(9), 1097-1106. Wei, C. , Caldarone, B.J. , King, S.L. , Stevens, T.R. & Picciotto, M.R. (2002). Effects of chronic nicotine on brain monoamines in mice. Nicotine and Tobacco Research Supplement. Caldarone, B.J. , Karthigeyan, K. , Wittmack, E.K. & Picciotto, M.R. (2001). Effects of oral antidepressant treatment in 3 animal models of depression in mice . Society for Neuroscience Abstract, 27. George, T.P. , Picciotto, M.R. , Verrico, C.D. & Roth, R.H. (2001). Effects of nicotine pre-treatment on dopaminergic and behavioral responses to conditioned fear stress in rats: Dissociation of biochemical and behavioral effects. Biological Psychiatry, 49(3), 300-306. Grady, S.R. , Meinerz, N.M. , Cao, J. , Reynolds, A. , Picciotto, M.R. , Changeux, J.-. , McIntosh, M.J. , Marks, M.J. & Collins, A.C. (2001). Nicotinic agonists stimulate acetylcholine release from mouse interpeduncular nucleus: A function mediated by a different nAChR than dopamine release from striatum. Journal of Neurochemistry, 76, 258-268. McKee, S. , Sinha, R. , Robinson, J. & O'Malley, S.S. (2001). Effects of family history of alcoholism, smoking status, and sex on subjective and motor responses to alcohol. Alcoholism: Clinical and Experimental Research, 25, 113a. Picciotto, M.R. (2001). Comparison of transgenic strategies in addiction research. Journal of Psychopharmacology, 15, A9. Picciotto, M.R. , Brunzell, D.H. , Zachariou, V. , Stevens, T.R. , King, S.L. & Caldarone, B.J. (2001). Nicotinic acetylcholine receptor knockout mice: Physiological and behavioral phenotypes and possible clinical implications. Pharmacology and Therapeutics, 92, 89-108. Schneider, T.R. , Salovey, P. , Pallonen, U. , Mundorf, N. , Smith, N.F. & Steward, W. (2001). Visual and auditory message framing effects on tobacco smoking. Journal of Applied Social Psychology, 31, 667-682. Staley, J. , Krishnan-Sarin, S. , Zoghbi, S. , Tamagnan, G. , Fujita, M. , Seibyl, J. , Maciejewski, P. , O'Malley, S.S. & Innis, R.P. (2001). Sex differences in [123I]beta-CIT SPECT measures of dopamine and serotonin transporter availability in healthy smokers and nonsmokers. Synapse, 41, 275-284. Zachariou, V. , Caldarone, B.J. , Weathers-Lowin, A. , George, T.P. , Elsworth, J.D. , Roth, R.H. , Changeux, J.-. & Picciotto, M.R. (2001). Nicotine receptor inactivation decreases sensitivity to cocaine. Neuropsychopharmacology, 24, 576-589. Zoghbi, S. , Tamagnan, G. , Fujita, M. , Baldwin, R. , Amici, L. , Tikriti, M.A. , Seibyl, J. & Innis, R.P. (2001). Metabolism of 5[I-123]Iodo-3(2(3)-azetidinylmethoxy) pyridine, a nicotinic acetylcholine receptor imaging agent, in non-human primates. Nuclear Medicine and Biology, 28, 91-96. Caldarone, B.J. , Duman, C.H. & Picciotto, M.R. (2000). Fear conditioning and latent inhibition in mice lacking the high affinity subclass of nicotinic acetylcholine receptors in the brain. Neuropharmacology, 39(13), 2779-2784. Caldarone, B.J. , George, T.P. , Zachariou, V. & Picciotto, M.R. (2000). Gender differences in learned helplessness behavior are influenced by genetic background. Pharmacology, Biochemistry & Behavior, 66(4), 811-817. George, T.P. , Verrico, C.D. , Picciotto, M.R. & Roth, R.H. (2000). Nicotinic modulation of mesoprefrontal dopamine neurons: pharmacologic and neuroanatomic characterization. J. Pharm. Exp. Therap., 295(1), 58-66. Marks, M.J. , Stitzel, J.A. , Grady, S.R. , Picciotto, M.R. , Changeux, J.-. & Collins, A.C. (2000). Nicotinic-agonist stimulated 86Rb+ and [3H]epibatidine binding of mice differing in Beta2 genotype. Neuropharmacology, 39(13), 2632-2645. Whiteaker, P. , Marks, M.J. , Grady, S.R. , Lu, Y. , Picciotto, M.R. , Changeux, J.-. & Collins, A.C. (2000). Pharmacological and null mutation approaches reveal nicotinic receptor diversity. European Journal of Pharmacology, 393, 123-135.